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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd302761ecc577c605f4a1189d3e2de3057d64a0e9cb5eb7a5000c10d3fba150' 
  AND token = 'nPxyq+TRII9onoNYik3dg46an0clvSZQleIT5tdnlyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}