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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6300f7149129ebacb6954dec280dc12f1eb0a436fea43aaf69831ac22307e760' 
  AND token = 'qlpJ+sx86E+3eiZPGsxrZCpP/g1hikzK6fWv1eF6W6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}