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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4392ae52ef6078f0e8a0151e9e016fa5f03fbfdde693559ca2028c0b8b89179f' 
  AND token = 'c4w8MlK6xdH8AyB9ngAUptJw3mKaev+hTd+kZMjTqjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}