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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '091bda40c23d073b4debda60324a437c6315c6e983161c1a6b68f186b60dc8e2' 
  AND token = 'aky/jUD3GqwbTll8SO8027SeeAT55tsDKmgpc2ugM5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}