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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50d7587cdb9c45caf5d83f81c0b8b449d767cb6e40488b578c358dc6e2da076' 
  AND token = 'uRloKQvUoM2inSXLmzus1iQr521vw1SzgNUlYgcO774=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}