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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a6e2dc6db4db6b49fd1d53a8cde0b2843fd3b2c93d19aad39680c4d3c474bf4' 
  AND token = 'ptBeb6jeTmCXahmrjza60YrIxNPPUQdEupas5mnbzPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}