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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed35395f96ebe07850f4f4f71b48ab66515cbf1e532c32e3314c0c4d4d7d312c' 
  AND token = 'S/62HDx43P7weo7L1sw9shYcfJDd3IcKYjUKplOntZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}