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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b8f6263101c0282c9f9d2953a0e289d0d36a3fe3bf43149b6a24271ee9a1809' 
  AND token = 'b/Dsuy+ZKpOcS4cvhbllJAdNbuex0dQNT7vAZczrl3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}