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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65eaedf2232b64cddd144714b024a57250a1cd8f7bf960971ee66982fc4ad271' 
  AND token = 'frxOACjeinjlOPJ20fnFOp0xTSz1TgWuGfh05njyPEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}