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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '019d33bd3b7da2d402fc13b8519e8d48313d1ebe789daaaa814c71cac6e571f5' 
  AND token = 'lsJbcdfK8qmu/Ig4ZaX9gx+l1wldU0Xk03mhe5XkVmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}