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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32a343b22144c0b7be349d6bf3098f3d319e8c8f221a3dbe05155fbb2cdd487f' 
  AND token = 'REqKBifA2XWEdqaR3v/K5Jy44nSlaV8j8q6TYAVZTAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}