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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c743cca35bd4d2998b9021cb26ea984cd5c6b7528e5f4f69f3eef234f87c7143' 
  AND token = 'TIbkPoT2XHW124MrKesnjh2X3m1J5fnNw82y5xKVxQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}