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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e0d227aa622da0c0ab64683617a8e6a155a81740a0f21101007eccea3ae139' 
  AND token = 'NzSQyKUAEOjr35reA6JhJmqClqpJFB6GsGefc70gaOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}