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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a5e6bc569eb3b4fa044301a33ec57357b18a7101a1400a6e95221380f8b449f' 
  AND token = '8ptTgncc049s5f8BYmsKeYuHwBBBBPZ/0MRSIglacmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}