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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61cdcffadcf406d5d0f1cdf6819a1862399c7d2a8a6b672b577604de7dd78dc1' 
  AND token = '/1LT+ayNi9R4FRDXS/mbF7JT0J4qj7y8pAhMD8hMOlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}