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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d5a9338e8836cd2764b34984f7b9d5403dc6d432ee1e75af92d99d4b3abe3a5' 
  AND token = 'kGq6WgtPUQNyOyM+MwzmbiKyB2WZuy9fa3l0cnTC2l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}