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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1b873abc1232d113068b85cb50127581c6020635be2849b997748ba8b00f53' 
  AND token = 'oLOoNW1hAzKCFdDjrwd8H0KhZiZKWJ6+G/Zpt8DFSoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}