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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49b6cc864ce8e73acc41586e0986af8f7256c2a2180be3ae8ce7de9e8107d76' 
  AND token = 'UImkx5fBubuOJX0sXb00liB5t/MquVIgQQlZNYIcjgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}