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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f27519bdd92e9b9a45eba0a78900af78b4e0f912606e7be018e089ac4e9c50d' 
  AND token = 'xJCTblxfqWFpUfR90GWNOhREvFlbfM1z6yYpd31dt88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}