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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7f482ea7e50a72d01739a5fff2a122262eb36fced124cc199cab948b26f1a67' 
  AND token = 'X+AccMsvTCZ3AmylZ6IkLQERUXH5QTIp+58cTTDSrKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}