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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '086719e5bd90ebf55b4c0c7b14760031b4de42a3375e43aace3f6e782434729c' 
  AND token = '11OAA3SwXcvStRtDqoek0jAh2SvzS+f4ZqQRWiJKVz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}