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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6262af52cdd7d4c77a8c9101e5803d5e93ed73e48f70adf614b822c8f07d45ab' 
  AND token = 'UF57Ln1DLmqVAuF67LI2/hHQHyS4Ij+3Gm9Tc0U9i7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}