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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df8f4a01b82084056c54a2bab7e4aa158147104d7629342500e87075f41d20f5' 
  AND token = '2HYCKZTIpZQooYUSSopwFXgTzqdSpU66ZYVC1PDQOlI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}