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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cfa3a0e4a63e7b70b530a0a30063df6036201c13edf70b27e6911b3422ad4f9' 
  AND token = 'nK1xIT1zxr3DG6CMh6yCxwjV9Dm/yU1syZ0+K4uOe5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}