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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97d2a3319ad1d6a89b7e4152e00e738758d9b1bb0e234a390949f09b2a1d3107' 
  AND token = 'ZhueSBWHgZKE9pCvOb4UeP8DqTW2a9BoVBRMWzkXdBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}