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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2bb7bd00fda207aee58a23be3ee29ae99e1437b7305b6b33ae49050697aaab4' 
  AND token = '9a1OEnjBlxasdOy2THO/AZ61T9wVBmsuYa3SVlyiPj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}