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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11512b6a44faeb3f7fee5a48fc7b9b878a0e3d56a1b5e5238674a4960211d7e8' 
  AND token = 'iaXEotmvkSvV0PeqZLyNzNGTJZkcRX5SYSIrsMr8bwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}