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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f177e14fb75c1a4f9b4325a272776874fe5d9c713b0d87d01913166fdd4f02fc' 
  AND token = 'QF0u1/XHveyc+EBneQg8LAbxKUzCNT7+d/JNQpYm55Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}