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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e3d14d4026a7c502ec1b889117c2cb7bb5ee029fe2f8ea184d3c8e82ea7464' 
  AND token = 'k+WoAkqkCGh9eWrI1iQs/NkJTI+iG+0aMv8kijc6sWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}