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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddc77f86e1c91fdf364331fcd6de69a8f73a0db16bb5c1010ceee27f7f0fa02' 
  AND token = 'jGmw2r7FmZQmPgGmkqeAg4qgp+pZl9Blbwod2sVE2Rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}