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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '417531d0c61bbae316192e619304807912040cc8006b01ab01a665ebcffb5165' 
  AND token = '+X+ysIygq7uHofw0P2/I14i3/q3Y58mlbxC61OsBM+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}