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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d76d95efb1ba9fdf2d1044f514df2cd744a759db10778ff5764a7e39ec52f0' 
  AND token = '2WgJ6Dl5vxdwiygVmdTe52eeUQg2q/3OyBJbQUG1C+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}