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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a10d26015739c70103581bc1eb636e252e3af6e9d94f20aa747d186b797a5c8' 
  AND token = 'EKAozuSQB9L9+HAr5tO+RzqIpuWB2cRdKWjkDCB8nsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}