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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2086bdc0b3a607d6fe3667970740bf0518908a21b8b57d161c2cbf768e9d65c' 
  AND token = 'V+Smio/2f4gZgo+8VEPsn9s136bk6Bwx2i+boDpxnV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}