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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cde778f8c264efae3f46af2c63d941ce01224e9920b28c8f83a860b21a2d83e0' 
  AND token = 'm/gVMtO2I8l7aTg1xacF39NKdIKDGhvu9/cP70pM6w8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}