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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a37a7e1dd7bf4d0e5299bbaf318ad1f18085a52574d580e15a97397a86c15a' 
  AND token = 'gR8C5X3sLaVdM83Nk8LcH+9URRYdmFv2zWPOlDIw9To=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}