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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c2cdbe890499bc5b4b1c41c46e532230df5964b2b8558dba3f073c26c564ad' 
  AND token = 'VBLdTcD6+tAfAnRM47aGfuNEFAyRCaIL5k9ofyEj8OY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}