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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '606a6cc777d849b09c6658548a9d39851b0a1a2f41ae444d6bd075cab435d833' 
  AND token = 'PCf5dSRAyGd1GPvf2i6c2w0bpVo+lxfgnjLA5bA/0tI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}