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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b9d48b00b8e06562e9b5ede9613a334dac000dff3043d1fcee6d2b729a0a23c' 
  AND token = 'Y4LGY4uQOP07ayrXwZ/np8eehGERwAwbpzCo56mA8Dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}