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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed01883c2e114c751a0d428b65c3eff079c4539e113b9977e91889db1dd5170' 
  AND token = 'TUuYA0gu6vWeJBHzRckF8P3wv8EzHRtQnQACduH2mm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}