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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b38a22932e30f29624270a32785798927d8d588efcb2bd3a52f86ec9f33b204' 
  AND token = 'XqFFDJ/7jvVKVk6CS/GS9IHZBxWjVrMtT020fOEAOYk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}