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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58b1a21c727afbc0b90995a5e4a441bcf488b59974ccc3f22f8732a59afde218' 
  AND token = 'E/vzY/HW06M6IuckSGOp/g0vR8g2pUP030qIeqUh7oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}