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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87cbe2546ccb188f893aa3bc7036dba42716259e3698b48e8e9cd612b6972994' 
  AND token = '8XbB5/v9PhG1A7tv2OSYF2TL+KAxWbmZ7ThXd19U0kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}