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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5972d35ebeb652e42c6ff27448167b1fcf935c5431197fc17d72bea3b517dade' 
  AND token = 'U4s/h6e+OspRujRtdJgtjZym/P2GkyAel9TMYNhUso0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}