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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a166631f0058324ec290c62ed6d703d2090a9f00b7d90a55012f63ab682f748a' 
  AND token = 'E+bpF7v7gweBh2R8FmnmZvW6S1ckgiOU+DeD9Fn4d0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}