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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '384e817e89110f7d3cde7322e4b3ec5fade4590e6a900b78f7b66909a33c6008' 
  AND token = 'OLggpGgaFHai76VckseSeG7RVS2YuBTPpsmLMlUjx70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}