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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ff71768fa7654be3c30e726fffecf68e453d3798b56608bc5d99d92427d5c3' 
  AND token = 'b3E2KH0qHSiqzA5BOZ6deQ+hyeXa/DYhQnS7oUODzZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}