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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5242f29f35990bebb764239d5c4d71e9055adebe879b78103d56dc715b671f' 
  AND token = '80a/jyNLQM4zqe3JVSmkfyDub7FWXdUrTIS55xYt3cA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}