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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c435e82de90acfe8d98eb84c6c905269beb7e5ff99ee9a46326d9e92475b422e' 
  AND token = 'pPwqNy53dsEqd4mSR/Qa4N3vkzHJX2hRe/5LEihz8eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}