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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b440c59b9c67d668f083d0506687964b50ecd98f337b0257c70c55a8cdd3e2f' 
  AND token = 'iG/AtU3fhX9ylyA8GF9mLUikz4E7jVvTe028T8N0ICs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}